5-[(S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl]-1-[(1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl]-1H-indole-2-carboxylic Acid

Orforglipron Intermediate;(S)-Orforglipron Carboxylic Acid Intermediate;GLP-1 Agonist API Intermediate (Indole-Oxadiazole Core)

CAS: 2212021-83-3

CAS:2212021-83-3

Chemical Formula:C22H25N3O5

Molecular Weight:411.46

Availability: R&D; Commercialization

Orforglipron Intermediate GLP-1 Agonist API Synthesis Supplier

Orforglipron Intermediate

⬤ CAS No.2212021-83-3

⬤ Packaging type:

20kg barrel;5kg barrel;1kg bag;500g bag ; Customized Packaging

Product Name5-[(S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl]-1-[(1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl]-1H-indole-2-carboxylic Acid
CAS No.2212021-83-3
Chemical FormulaC22H25N3O5
Molecular Weight411.46
Related CategoriesOrforglipron Intermediate
Density 1.48±0.1 g/cm3(Predicted)
Acidity coefficient (pKa) 4.55±0.30(Predicted)
InChIKey VWANSYGDVGYGTG-ODJFAWIYNA-N
NoteThis product is specifically used as a chemical synthesis intermediate for orforglipron and other GLP-1 receptor agonist drugs and is not suitable for direct drug preparation or clinical use.
Core drug synthesisOur product is a key intermediate of Orforglipron and is mainly used for: synthesize GLP-1 receptor agonist drugs, targeted treatment of type 2 diabetes and obesity.
R&D and extended applicationsAs a structural template for optimizing the activity and pharmacokinetic properties of GLP-1 analogs.

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April 27, 2024

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