Sacubitril-Valsartan Sodium Salt; Valsartan/Sacubitril; Heart Failure Drug
CAS:936623-90-4
CF:C48H55N6O8Na3·2.5H2O
MW:957.99
Availability: R&D; Commercialization
⬤ CAS No. 936623-90-4
⬤ Packaging type：
20kg barrel；5kg barrel；1kg bag；500g bag ; Customized Packaging
| Product Name | Sacubitril Valsartan |
| Alternative Names | LCZ696, Entresto, Sacubitril mixture with Valsartan |
| CAS No. | 936623-90-4 |
| Molecular Formula | C48H55N6O8Na3·2.5H2O (Approximate, depending on salt form) |
| Molecular Weight | 957.99 (Approximate, including salts and hydrates) |
| Manufacturer | Shandong Tianming Pharmaceutical Group |
| Indication | For the treatment of chronic heart failure to reduce the risk of cardiovascular death and heart failure hospitalization |
| Formulation | Film-coated tablets |
| Active Ingredient | Sacubitril valsartan sodium |
| Dosage Strength | 100 mg (Sacubitril 49 mg / Valsartan 51 mg) |
| Packaging | Multiple packaging options available, e.g., bottles |
| Storage | Typically at room temperature with protection from moisture and light |
| Solubility | Ethanol: 9 mg/mL, H2O: 92 mg/mL, DMSO: 45.45 mg/mL (Approximate, can vary) |
| Safety Assessment | Demonstrated good safety profile in large-scale clinical trials with no increase in adverse event rates. |
| Precautions | Monitor blood pressure, renal function, and electrolyte levels. Avoid drug interactions. |
| Special Populations | Adjust dosage or use with caution in patients with renal or hepatic impairment, and in the elderly. |
| Adverse Reactions | May include hypotension, hyperkalemia, etc. Monitor closely for symptoms. |
| Contraindications | Pregnant women, patients with a history of angioedema involving the throat. |
| Product Name | Nornicotine |
| Storage Conditions | Store at -20°C |
| Solubility | ≥45.05 mg/mL in DMSO; ≥11.28 mg/mL in water; ≥28.5 mg/mL in ethanol |
| Form | Solid |
| Color | White to light yellow |
Exceptional Product Quality
“We have been sourcing pharmaceuticals from Tianming Pharmaceutical for several years now, and their product quality has consistently exceeded our expectations. Each batch undergoes rigorous testing, ensuring we receive only the highest quality products. This reliability has significantly contributed to our trust and satisfaction with their services. Highly recommended!”
June 15, 2023
Outstanding Technical Guidance
“The technical guidance provided by Tianming Pharmaceutical’s team has been invaluable to our research and development projects. Their experts are knowledgeable, responsive, and always willing to assist with detailed explanations and support. Their guidance has enabled us to optimize our processes and achieve remarkable results. We couldn’t ask for a better partner.”
June 15, 2023
Superior Service Experience
“Our experience with Tianming Pharmaceutical has been nothing short of excellent. Their customer service team is exceptionally responsive and dedicated to meeting our needs. From initial consultation to after-sales support, they have provided seamless, professional service. Their commitment to customer satisfaction is truly commendable.”
June 15, 2023
Precise Product Specifications
“Tianming Pharmaceutical has impressed us with their adherence to precise product specifications. Each order is meticulously packaged and delivered exactly as requested, ensuring that we receive products that perfectly meet our requirements. Their attention to detail and commitment to accuracy have made them a trusted supplier for our business.”
June 15, 2023
Hechi Vice Mayor Chen Zhijie toured Tianming Pharmaceutical’s facilities, praising its R&D strength and the “Jinan R&D + Hechi production” model.
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